A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Olanzapine oral tablet may cause drowsiness. This drug can also cause other side effects. If these effects are mild, they may go away within a few days or a couple of weeks.
Call your doctor right away if you have serious side effects. Serious side effects and their symptoms can include the following:. Disclaimer: Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects.
This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare professional who knows your medical history.
Olanzapine oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully.
Benzodiazepines, such as diazepam. Increased side effects can include orthostatic hypotension, drowsiness, tiredness, and dizziness. Your doctor will monitor you closely during therapy. Blood pressure medications. They also include angiotensin-converting enzyme ACE inhibitors, such as benazepril, captopril, or enalapril.
Increased side effects can include a dangerous decrease in your blood pressure. To help avoid this, your doctor may decrease your olanzapine dosage.
Anticholinergics, such as atropine or dicyclomine. Increased side effects can include constipation, trouble urinating, and falls. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare professional about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.
Taking it again could be fatal cause death. Avoid the use of drinks that contain alcohol while taking olanzapine. Drinking alcohol while taking olanzapine raises your risk of orthostatic hypotension. When this occurs, your blood pressure drops too low after you stand up after sitting or lying down.
Drinking alcohol can also increase the drowsiness caused by olanzapine. If you drink alcohol, talk with your doctor about whether this drug is safe for you. Olanzapine raises the risk of death in seniors ages 65 years or older with dementia-related psychosis. Most of these deaths are caused by heart problems such as heart failure, or infectious conditions such as pneumonia.
For people with seizures: Olanzapine can cause seizures. Tell your doctor if you have a history of seizures or epilepsy. For people with diabetes or high sugar levels: Olanzapine can increase your blood sugar levels. Your doctor should check your blood sugar levels before and during treatment with this drug.
They may need to adjust the dosage of any diabetes medications you take. While you take this drug, watch for symptoms of high blood sugar.
These can include feeling very thirsty, needing to urinate often, having an increased appetite, or feeling weak. If you have these symptoms, check your fasting blood sugar level and call your doctor. The College of Psychiatric and Neurologic Pharmacists disclaims any and all liability alleged as a result of the information provided herein.
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Advocacy Crisis Intervention. Advocacy State Fact Sheets. Advocacy Public Policy Reports. Olanzapine Zyprexa. Know the warning signs Learn the common signs of mental illness in adults and adolescents. Mental health conditions Learn more about common mental health conditions that affect millions.
Symptoms of schizophrenia include: Hallucinations — imagined voices or images that seem real Delusions — beliefs that are not true e. Olanzapine is also FDA approved for the following indications: Acute treatment of manic or mixed episodes of bipolar disorder Maintenance long-term treatment of bipolar disorder Acute treatment of agitation in schizophrenia and bipolar disorder This medication sheet will focus primarily on schizophrenia. Missing doses of olanzapine may increase your risk for a relapse in your symptoms.
Symptoms of your condition that bother you the most If you have thoughts of suicide or harming yourself Medications you have taken in the past for your condition, whether they were effective or caused any adverse effects If you ever had muscle stiffness, shaking, tardive dyskinesia, neuroleptic malignant syndrome, or weight gain caused by a medication If you experience side effects from your medications, discuss them with your provider.
Some side effects may pass with time, but others may require changes in the medication. Any psychiatric or medical problems you have, such as heart rhythm problems, long QT syndrome, heart attacks, diabetes, high cholesterol, or seizures If you have a family history of diabetes or heart disease All other medications you are currently taking including over the counter products, herbal and nutritional supplements and any medication allergies you have Other non-medication treatment you are receiving, such as talk therapy or substance abuse treatment.
Your provider can explain how these different treatments work with the medication. If you are pregnant, plan to become pregnant, or are breast-feeding If you smoke, drink alcohol, or use illegal drugs How Should I Take Olanzapine? Olanzapine tablets are usually taken 1 time per day with or without food. Talk to your doctor first if you want to go onto a lower dose or to stop taking olanzapine.
The antipsychotic medicine you are prescribed will depend on the type of symptoms you have, how bad your symptoms are, any other medical conditions you have and how well your medicine works for you. You may have to try a few before you find the antipsychotic medicine that is right for you. It can take time to find the right type and dose to manage your symptoms. Different antipsychotic medicines have different side effects. Lithium is usually the first medicine used to treat bipolar disorder.
Lithium is a mood stabiliser, which means it helps to balance your mood and control symptoms of mania as well as depression. Olanzapine also helps with symptoms of mania. However, you will need to take it with another medicine to also manage your depression symptoms. You can discuss with your doctor which treatment will be best for you.
It will depend on the type of symptoms you have, any other medical conditions you have and whether you might be more likely to have side effects with some medicines. Your doctor will use other medicines as a first choice if you have anxiety. If you drink alcohol while taking olanzapine it may make you feel sleepy and unsteady on your feet. Drinking alcohol every day or in large amounts can make your symptoms worse.
It also makes it harder for olanzapine to work properly. You will not usually lose weight on olanzapine. It can make you feel more hungry than usual, so you may put on weight.
Try to eat a healthy balanced diet, without increasing your portion sizes. Do not snack on foods that contain a lot of calories, such as crisps, cakes, biscuits and sweets. If you feel hungry between meals, eat fruit and vegetables and low-calorie foods. If you are worried about gaining or losing weight while taking olanzapine, talk to your doctor or pharmacist. Apart from limiting alcohol, you can eat and drink normally while taking olanzapine.
If you have an increased appetite, try to eat a healthy balanced diet without increasing your portion sizes. Olanzapine will not affect any type of contraception, including the combined pill or emergency contraception. Olanzapine can affect your hormones and sometimes causes sexual problems, such as less interest in sex reduced libido in men or women, and problems getting an erection.
It can also affect periods. If you would like to start a family, then talk to your doctor if you have any of these problems or if you have any concerns.
Olanzapine is a type of medicine called an antipsychotic. Most antipsychotic medicines can cause sexual problems, but some are more likely to cause problems than others. If you feel you have a sexual problem of any kind while taking olanzapine, including less interest in sex reduced libido or problems getting an erection, talk to your doctor.
Your doctor will be able to help you and may change your olanzapine treatment so that the sexual problems improve or go away. Olanzapine can make you feel sleepy. If this happens to you, do not drive, ride a bike or use tools or machinery until you feel better. Some people find it hard to concentrate while they are taking olanzapine. When you first start taking it, it's a good idea to stop driving and cycling for the first few days until you know how the medicine makes you feel.
Page last reviewed: 27 July Next review due: 27 July Olanzapine - Brand names: Zyprexa, Zentiva On this page About olanzapine Key facts Who can and cannot use olanzapine How and when to take olanzapine Side effects How to cope with side effects of olanzapine Pregnancy and breastfeeding Cautions with other medicines Common questions about olanzapine. About olanzapine Olanzapine helps to manage symptoms of mental health conditions such as: seeing, hearing, feeling or believing things that others do not, feeling unusually suspicious or having muddled thoughts schizophrenia feeling agitated or hyperactive, very excited, elated, or impulsive mania symptoms of bipolar disorder If you have bipolar disorder, olanzapine can also stop your mania symptoms coming back.
Olanzapine is only available with a prescription. Olanzapine does not work straight away. It may take several days, or even weeks, for some of your symptoms to start improving.
Soon after you first start taking olanzapine, before your other symptoms improve, it may make you feel more relaxed and calm. Common side effects include: feeling sleepy, feeling dizzy, and constipation. It works by affecting the naturally occurring chemical messengers in your brain neurotransmitters , like dopamine and serotonin. Below are a number of topics that may be helpful in understanding more about Zyprexa withdrawal, including what Zyprexa does to the brain, interactions with other drugs, and more.
Zyprexa has a known chemical structure which determines or models how the drug is manufactured in the lab. It has a molecular weight of But beyond the recipe as such, there is little known about how exactly the drug works within the brain and central nervous system. We do know that Zyprexa is a member of a class of drugs called thienobenzodiazepines. This tells us that Zyprexa is an antipsychotic medication that is similar to benzodiazepines, both being gabaminergic in effect.
However, Zyprexa additionally deflects or blocks many other types of brain chemicals besides GABA, including dopamine. Therefore, Zyprexa allows numerous types of neurotransmitters to accumulate at receptor sites. More research needs to be done to understand the mechanisms of action of drugs like Zyprexa more thoroughly.
When a person begins a prescription of Zyprexa, the central nervous system and the brain will undergo some changes and reactions influencing certain natural chemicals that the body creates called neurotransmitters. There is more to be known about exactly how Zyprexa impacts these factors. The same can be generally said regarding every other drug that is on the market today.
Taking more than one drug simultaneously could change the way the drugs act in the CNS, either increasing or decreasing their effects. For example, alcohol and other psychoactive or medicinal drugs can interact with olanzapine and may make a person so drowsy that they should not operate machinery or drive a car.
Smoking cigarettes can dilute the concentration of olanzapine in the blood, as another example. Always inform your prescriber of any drug use and ask for information about potential interactions that may occur because of other drugs your doctor prescribes.
After ingesting Zyprexa, metabolites can test positive in the urine for approximately days. However, this time period may have little relation to the time it may take to fully adjust to being off Zyprexa. There is a high probability that affected receptors upregulated themselves, in response to the drug. It would follow that a person could experience some degree of over-stimulation, including manic symptoms, as a result of the neuroadaptive characteristics induced by the drug.
The time needed for these receptors to return to normal is indefinite, depending on such factors as genetics, length of use, dietary habits including caffeine or other stimulants, and could take months to years. A person should never abruptly stop taking Zyprexa as the shock to the body can be severe and intolerable.
Even with a slow taper, especially without proper support, withdrawals can tend to be long-lasting, and near to impossible to tolerate. Where the drug was taken long-term, seek professional help to avoid lingering Zyprexa withdrawal symptoms. These can last for weeks, months, or even years without adequate support and Zyprexa withdrawal protocols in place.
Sometimes antipsychotic drug withdrawals can be severe and last for weeks or months, even after only a few weeks of taking these medications.
Zyprexa affects a wide number of neurotransmitter receptors in the body and may have an initial effect of sedation or calming. Also, for those with depression, perhaps it will garner a temporary lift or rise in mood. However, the central nervous system can become altered after the regular use of such a drug, resulting in drug dependence. The side effects that can present with Zyprexa can also be challenging, and a person may opt to come off the drug where the benefits of the medication are not outweighing the negatives.
When this occurs, especially when disadvantaged with multiple health challenges, there could be quite a challenge to come off the drug. Families often are hit the hardest when a loved one is experiencing such difficulties. There may be a better choice than continuing on a path where hope is all but lost and the pain and suffering seem to go on without abatement.
It is difficult to watch a loved one suffer. Enrolling at Alternative to Meds Center provides stress-free, superlative care for anyone seeking to recover from Zyprexa side effects and Zyprexa withdrawals. Our center is staffed with medical professionals and caregivers who understand medication withdrawal and the depth and breadth of the challenges. Compassionate and efficient care is the hallmark of our center.
Please visit our services overview page for more details on protocols used in our programs, and for pictures of the center. You may have questions relating to your insurance coverage, or you may need other information that will help in making treatment decisions. We are here to help you. Please feel free to contact us at Alternative to Meds Center for more information on these matters, and about the alternatives and protocols used in our individually tailored, safely monitored, and comfortable Zyprexa withdrawal treatment programs.
Pharmacokinetic and pharmacodynamic profile. Clin Pharmacokinet. PMID: FDA drug label Zyprexa olanzapine [online [cited Dec 3] 6. J Pediatr Pharmacol Ther. Psychother Psychosom.
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